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Understanding
9/11Movement of ammonia from peripheral tissues to the liver
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- Publication date
- 2021-09-24
- Usage
- Attribution 4.0 International
- Topics
- Cell Biology, Genetics, and Biochemistry for Pre-Clinical Students
- Language
- English
- Item Size
- 414.1K
This image is part of a series that was created for an open textbook, Cell Biology, Genetics and Biochemistry for PreClinical Students. The textbook will be available Late 2021.
Preferred citation:
Kindred Grey (2021). "Movement of ammonia from peripheral tissues to the liver." CC BY 4.0.
Alternative text:
Most tissues: Glutamate arrow with enzyme glutamine synthetase and ATP + NH3 arrow ADP + Pi to glutamine. Liver: Glutamine from most tissues arrow with enzyme glutaminase and H2O arrow NH3 arrow urea to glutamate. Circular arrows between glutamate and -ketoglutarate with enzyme glutamate dehydrogenase and loss of NH3. Alanine arrow touching arrow between α-ketoglutarate and glutamate with enzyme alanine aminotransferase to pyruvate arrow glucose. Muscle: Glucose from liver arrow glucose arrow pyruvate arrow with enzyme alanine aminotransferase to alanine arrow to liver. Pathway labeled glucose alanine cycle. Glutamate arrow with alanine aminotransferase to α-ketoglutarate arrow with enzyme glutamate dehydrogenase to Glutamate. Amino acids arrow NH3 arrow to arrow between α-ketoglutarate and glutamate.
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